Represented by the Division of Research and Publications, its special functions are to elaborate and develop projects both in vivo (developed and developing) and in vitro (hidrodynamics performance). It aims to improve quality and control of the company’s products already in the market as well as new ones. It is also involved in orienting, writing, editing, analyzing and reviewing scientific papers and preparing the necessary documents for the registration of products at the Ministry of Health. It provides information about company products by mail, telephone, labels, catalogs and scientific texts. Besides giving assistance in marketing videotapes and photographic arrangements for scientific events, it gives assistance to medical centers such as in the filling out of patient charts, abstracts for congresses, curriculum vitae, bibliographic investigation in the medical field, printing scientific papers and creating, producing and assembling slides. It also keeps in touch with national and international suppliers as well as with maintenance teams of equipment utilized for in vitro tests. There are ten professionals in this area who are medical school, biology, mechanical engineering, liberal arts and law graduates.
A technical-scientific cooperation project with the Friedrich-Alexander University, Erlangen, Germany and Biotronik S.A with the development of Cardiomyostimulant (Myos) for cardiomyoplastic surgeries as an alternative to transplantation.
Research and Development Program of biomaterials based on Collagen and Polyurethane - development of new biophilization processes of Bovine pericardium to make valvular cardiac prostheses - CNPQ/PADCT II (process # 620.228/91-1) Division of Research and Publications of Braile Biomedica and Department of Chemistry and Molecular Physics of IQSC - USP.
Project "Collagen Biomaterials in Association with synthetic polymers and Calcium Phosphate Salts to be used in Medicine and Odontology" CNPQ / PADCTII (process # 62.001/96-8. Department of Chemistry and Molecular Physics of IQSC-USP and Division of Research and Publications of Braile Biomedica).
Research project "myocardial protection obtained by continuous or discontinuous infusion of cardioplegic solution in an isolated heart circuit of guinea pig (cavia porcellus)" (DPP / Braile Biomedica da Faculdade de Medicina de São José do Rio Preto - Famerp );
Comparative Study of the hydrodynamic performance among in vitro biological valves: bovine x porcine pericardium (Division of Research and Publications of Braile-Biomedica and Department of Chemistry of IQSC/USP).
"Development of Biological and Mechanical Cardiac Valves - CNPq/ Rhae (Process # 610,048/96-1-Area of Special Materials (Division of Research and Publications of Braile-Biomedica and Department of Chemistry of IQSC/USP).
"Program of Development and Construction of Bovine Pericardium and Mechanical Cardiac Valves - FAPESP (Process # 96/2455-8), Institute of Chemistry of São Carlos and Braile Biomedica S/A.
The pulse duplication system Shelhihg incorporates two amplifiers, an electromagnetic flowmeter, a differential pressure transducer, a PC AT 286 computer, a laser printer and an electromagnetic sensor to measure flow. The system may be shaped to test valves in the mitral or aortic position, depending on the sensor position and it analyzes the valve automatically according to the record for mitral or aortic based on the information supplied by the operator.
Bovine pericardium bioprostheses undergo 5 phases of operation equivalent to 60, 70, 80, 90 and 100 beats per minute with ejection volume programmed for 90 ml per beat therefore progressively increasing the simulated cardiac output. The system evaluates:
The bibliographic service utilizes two sources: Medline and Lilacs accessed through two "on line" systems BIREME (Latin American and Caribbean Center of Information in Health Sciences) and CD- ROM Physician’s Silver Platter of Cardiology.
For the production of slides, Braile Biomedica has a computer system, which includes a Digital Palette, a slide scanner; a scanner for digital images and up-to-date software that allow the production of excellent quality colored slides. Braile Biomedica also has a laboratory for the development of slides.
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